Evaporation process of hydrogen peroxide development considerations
In our recent webinar"In the facilities and airtight system effectively H2O2Biological purification", we don't have time to answer all the questions, so we then reply by email.In this blog, we share questions and answers three categories: biological purification process development, low PPM measurement and condensation.
Biological purification process
Q: representative place is enough to prove that biological purification ability?
A: I suppose you want to ask is, whether the representative location measured the vaporization H2O2Is enough to prove that have biological purification.The answer is, once a process has experienced after verification cycle development, so the appropriate monitoring is enough, until the need for the next cycle to certification.But the vaporization H2O2Monitoring of on-line monitoring does not replace the use of chemical, biological or enzymatic indicators to verify this process.
Q: how PPM (in hydrogen peroxide concentration level meter) associated with effective biological purification?
A: temperature, vaporizing H2O2PPM level and the exposure duration of combination can be used to evaluate the effectiveness of biological purification process.Other variables, such as material, temperature, relative humidity,The relative degree of saturation) have correlation.But it is important to understand between them are interrelated.
Q: PPM concentrations are associated with the biological purification of effective?I ask is: because sometimes with low concentration of H2O2Circulation process will pass, and sometimes high concentrations of H2O2PPM cycle will fail...
A: the vaporization H biological purification process2O2PPM concentration depends on many variables, including the type of microbes and biological purification space as well as the challenges associated with space, such as the object.Some areas or process may require a low PPM level issued a longer duration, and other area or procedure is required in high PPM level of shorter duration.There is no single correct way.You are using should be in the process of the typical development under the condition of normal cycle.
Q: does altitude affect the humidity in the process of biological purification and saturation?
Answer: yes, altitude does affect the relative humidity, which affect the relative degree of saturation.Relative humidity and the relative degree of saturation can water and vaporizing H2O2Relative to the total of each gas saturation vapour pressure (air in a certain temperature can accommodate the amount of gas) of partial pressure.This relationship has a linear relation with pressure change, so need correction in the process of measuring the altitude pressure drop.
The question: why does not meet 1 PPM concentration, at the end of the evaporation cycle, during and after aeration, H2O2Concentration changes?
A: aeration time owing to the different regions, and have many possible variables.Webinar provided in the sample is a basic representation.1 PPM limit value is 8 hours working days exposed safety instruction, sometimes even the target in the process of aeration.Different factors will affect the target level of aeration, namely materials, desorption, condensation and chemical compatibility.Sometimes, aeration goal is vaporized H2O2The PPB level.
Q: why will the vacuum evaporation of H2O2Used for the sterilization application?
A: vacuum conditions usually with vaporizing H2O2Transmission and aeration process.One way is to use deep vacuum will liquid hydrogen peroxide from a disposable cartridge, after heating evaporator, and then into the sterilization chamber after evaporation.
In another way, using a slight negative pressure (vacuum) through the carrier (such as air) will vaporize H2O2Introduced the sterilization room.Under the vacuum cycle may also have other benefits and matters needing attention.Pretty big suction also typically used for aeration.
Q: you must hold the conditions at 100% saturation of how long to get effective purification effect?
A: the length of the purification of cycle phase will be different, depending on the process of development of multiple variables.Factors to consider include: the type of disinfection of space and volume, the type of microbes to neutralize and space existing in the content and materials.The process of a typical time difference is very big.Biological purification process, for example, the room may need 4 to 24 hours, and isolator biological purification process may only take 1-4 hours.
Q: how much each biological purification process consume liquid peroxide have a rule of thumb?I can think of is 35% or 50% H2O2The number of per cubic meter of ml.Obviously, there are a number of factors: to purify the shape of the room or item and reducing level of the record, but if you feel that also need to consider what factors, I would be very interested.
A: unfortunately, I have no good answer of your question, because we use the type of generator is customized, and I don't know whether we have followed the density of its liquid2O2The consumption.In addition, the output of the steam generator and flow velocity are different, so it is difficult to give an answer, but I suggest to contact evaporator manufacturers.Their production and sales of vaporizing H2O2Products and services, is likely to provide better information for you.
Low PPM measurement
Q: H2O21 PPM for the European standard?
A: the European chemicals agency ECHA have a document assessment"On sale in the market and use of biological xiaosha products / 528 (eu) regulations 2012"
In the United States, ACGIH, OSHA and the national institute for occupational safety and health (NIOSH) will be the daily average occupational exposure limit is 1 PPM.
Q: how is visa, hydrogen peroxide probe measurement of low concentration?
A: at present,HPP270 productsMinimum measurable to 0 PPM, minimum accuracy of + / - 10 PPM.Therefore, visa, the company does not provide for low concentration vaporizing H2O2Solutions designed for the measurement.There are many solutions on the market, I will provide you with the reference material, in order to help you more in-depth understanding of the low level measurements.
Q: what if HPP270 measured the lowest levels for 10 PPM, how do we know when the operator can be safely again into the area has been purified?
A: HPP270 series probe designed for online, process level measurement is designed.These measurements can be used to manage vaporizing H2O2In the concentration of purification stage.HPP270 probe does not apply to safe level measurement.The duration of the aeration (after cycle development and validation) can explain the evacuation time, probe the real-time measurement and HPP270 series estimate the rate of change of can help do this.Currently, there are other low-level measurement options.
condensation
Q: what kind of method is more effective in the biological purification: dry or wet concentration (visible)?
Answer: wet and dry vaporization H vaporization2O2The effectiveness of the biological decontamination is a controversial topic.This is another should be determined by the process development projects.Usually, visa to pull sensor is the ideal choice for the two cases, even in high condensation process can provide accurate and stable measurement results.Condensation is why HPP270 probe provides relative saturation values.This is to make us to estimate when the cooling parameters.
Q: by atomizer nozzle jet H2O2Whether for condensation?
Answer: micro condensation is through careful to balance the air relative humidity, on the surface of the space and space in the relative degree of saturation and temperature conditions.However, visa not production evaporator or atomizer products of the company, so I cannot comment atomizer transmission capacity, because most of our experience are associated with hydrogen peroxide vaporization.
Q: whether recommend condensation in the process?
Answer: the disputes in the scientific community, there is no clear consensus.In the process of micro condensation, actually in the process of the condensate can form invisible, but it is in the submicron level, invisible to the naked eye.This is done by relatively saturation is very close to 100%.Scientific papers show that the hydrogen peroxide micro condensation in biological purification is necessary, and micro condensation may also occur in the drying process.Some studies focus on similar process with the process of your own, we recommend that you see this sort of research.
